Dual p38/JNK Mitogen Activated Protein Kinase Inhibitors Prevent Ozone-Induced Airway Hyperreactivity in Guinea Pigs

Ozone exposure causes airway hyperreactivity and increases hospitalizations resulting from pulmonary complications. Ozone reacts with the epithelial lining fluid and airway epithelium to produce reactive oxygen species and lipid peroxidation products, which then activate cell signaling pathways, inc...

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Detalles Bibliográficos
Autores principales: Verhein, Kirsten C., Salituro, Francesco G., Ledeboer, Mark W., Fryer, Allison D., Jacoby, David B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3776780/
https://www.ncbi.nlm.nih.gov/pubmed/24058677
http://dx.doi.org/10.1371/journal.pone.0075351

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3776780/
https://www.ncbi.nlm.nih.gov/pubmed/24058677
http://dx.doi.org/10.1371/journal.pone.0075351

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