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May Salivary Gland Secretory Proteins from Hematophagous Leeches (Hirudo verbana) Reach Pharmacologically Relevant Concentrations in the Vertebrate Host?

Saliva of hematophagous leeches (Hirudo sp.) contains bioactive proteins which allow the leech proper feeding and storage of ingested blood, but may also exert effects in the host. Leech therapy is used to treat many different ailments in humans, although only a small fraction of salivary proteins a...

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Detalles Bibliográficos
Autores principales: Lemke, Sarah, Müller, Christian, Lipke, Elisabeth, Uhl, Gabriele, Hildebrandt, Jan-Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3776796/
https://www.ncbi.nlm.nih.gov/pubmed/24058492
http://dx.doi.org/10.1371/journal.pone.0073809