Next-Generation Sequencing of HIV-1 RNA Genomes: Determination of Error Rates and Minimizing Artificial Recombination

Next-generation sequencing (NGS) is a valuable tool for the detection and quantification of HIV-1 variants in vivo. However, these technologies require detailed characterization and control of artificially induced errors to be applicable for accurate haplotype reconstruction. To investigate the occu...

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Detalles Bibliográficos
Autores principales: Di Giallonardo, Francesca, Zagordi, Osvaldo, Duport, Yannick, Leemann, Christine, Joos, Beda, Künzli-Gontarczyk, Marzanna, Bruggmann, Rémy, Beerenwinkel, Niko, Günthard, Huldrych F., Metzner, Karin J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3776835/
https://www.ncbi.nlm.nih.gov/pubmed/24058534
http://dx.doi.org/10.1371/journal.pone.0074249