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Next-Generation Sequencing of HIV-1 RNA Genomes: Determination of Error Rates and Minimizing Artificial Recombination
Next-generation sequencing (NGS) is a valuable tool for the detection and quantification of HIV-1 variants in vivo. However, these technologies require detailed characterization and control of artificially induced errors to be applicable for accurate haplotype reconstruction. To investigate the occu...
Autores principales: | Di Giallonardo, Francesca, Zagordi, Osvaldo, Duport, Yannick, Leemann, Christine, Joos, Beda, Künzli-Gontarczyk, Marzanna, Bruggmann, Rémy, Beerenwinkel, Niko, Günthard, Huldrych F., Metzner, Karin J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3776835/ https://www.ncbi.nlm.nih.gov/pubmed/24058534 http://dx.doi.org/10.1371/journal.pone.0074249 |
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