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Runx1 Is Critical for PTH-induced Onset of Mesenchymal Progenitor Cell Chondrogenic Differentiation

Parathyroid hormone (PTH) plays a critical role in the regulation of chondrogenesis. In this study, we have found for the first time that Runt-related transcription factor 1 (Runx1) contributes to PTH-induced chondrogenesis. Upon PTH treatment, limb bud mesenchymal progenitor cells in micromass cult...

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Detalles Bibliográficos
Autores principales: Wang, Jinwu, Wang, Xudong, Holz, Jonathan D., Rutkowski, Timothy, Wang, Yongjun, Zhu, Zhenan, Dong, Yufeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3776859/
https://www.ncbi.nlm.nih.gov/pubmed/24058535
http://dx.doi.org/10.1371/journal.pone.0074255