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Dynamically correlated mutations drive human Influenza A evolution

Human Influenza A virus undergoes recurrent changes in the hemagglutinin (HA) surface protein, primarily involved in the human antibody recognition. Relevant antigenic changes, enabling the virus to evade host immune response, have been recognized to occur in parallel to multiple mutations at antige...

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Detalles Bibliográficos
Autores principales: Tria, F., Pompei, S., Loreto, V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3776956/
https://www.ncbi.nlm.nih.gov/pubmed/24048220
http://dx.doi.org/10.1038/srep02705