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Subcutaneous administration of rituximab (MabThera) and trastuzumab (Herceptin) using hyaluronidase
BACKGROUND: Rituximab and trastuzumab were the first therapeutic monoclonal antibodies (mAbs) approved in oncology. Both antibodies are delivered by the intravenous (IV) route, but recently subcutaneous (SC) formulations have been developed. Subcutaneous administration of mAbs can offer substantial...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Nature Publishing Group
2013
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3776971/ https://www.ncbi.nlm.nih.gov/pubmed/24002601 http://dx.doi.org/10.1038/bjc.2013.371 |