Ranibizumab efficiently blocks migration but not proliferation induced by growth factor combinations including VEGF in retinal endothelial cells

BACKGROUND: Proliferation and migration of retinal endothelial cells (REC) are associated with the development of proliferative diabetic retinopathy. REC proliferation is stimulated by isoforms of vascular endothelial growth factor-A (i.e., VEGF(121) and VEGF(165)), basic fibroblast growth factor (b...

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Detalles Bibliográficos
Autores principales: Deissler, Heidrun L., Deissler, Helmut, Lang, Gerhard K., Lang, Gabriele E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2013
Materias:
Basic Science
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3777160/
https://www.ncbi.nlm.nih.gov/pubmed/23760670
http://dx.doi.org/10.1007/s00417-013-2393-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3777160/
https://www.ncbi.nlm.nih.gov/pubmed/23760670
http://dx.doi.org/10.1007/s00417-013-2393-5

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