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The anti-diabetic drug metformin does not affect bone mass in vivo or fracture healing

SUMMARY: The present study shows no adverse effects of the anti-diabetic drug metformin on bone mass and fracture healing in rodents but demonstrates that metformin is not osteogenic in vivo, as previously proposed. INTRODUCTION: In view of the increased incidence of fractures in patients with type...

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Detalles Bibliográficos
Autores principales: Jeyabalan, J., Viollet, B., Smitham, P., Ellis, S. A., Zaman, G., Bardin, C., Goodship, A., Roux, J. P., Pierre, M., Chenu, C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer London 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3777188/
https://www.ncbi.nlm.nih.gov/pubmed/23644877
http://dx.doi.org/10.1007/s00198-013-2371-0