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High Expression of H3K27me3 Is an Independent Predictor of Worse Outcome in Patients with Urothelial Carcinoma of Bladder Treated with Radical Cystectomy

It has been suggested that trimethylation of lysine 27 on histone H3 (H3K27me3) is a crucial epigenetic process in tumorigenesis. However, the expression pattern of H3K27me3 and its clinicopathological/prognostic significance in urothelial carcinoma of bladder (UCB) are unclear. In this study, upreg...

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Detalles Bibliográficos
Autores principales: Liu, Jianye, Li, Yonghong, Liao, Yiji, Mai, Shijuan, Zhang, Zhiling, Liu, Zhouwei, Jiang, Lijuan, Zeng, Yixin, Zhou, Fangjian, Xie, Dan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3777191/
https://www.ncbi.nlm.nih.gov/pubmed/24093096
http://dx.doi.org/10.1155/2013/390482