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Energetic role of the paddle motif in voltage gating of Shaker K(+) channels
Voltage-gated ion channels underlie rapid electric signaling in excitable cells. Electrophysiological studies have established that the N-terminal half of the fourth transmembrane segment ((NT)S4) of these channels functions as the primary voltage sensor, whereas crystallographic studies have shown...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3777420/ https://www.ncbi.nlm.nih.gov/pubmed/23542156 http://dx.doi.org/10.1038/nsmb.2535 |