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Signal regulatory protein-α interacts with the insulin receptor contributing to muscle wasting in chronic kidney disease

Insulin resistance from chronic kidney disease (CKD) stimulates muscle protein wasting but mechanisms causing this resistance are controversial. To help resolve this, we used microarray analyses to identify initiators of insulin resistance in the muscles of mice with CKD, glucose intolerance and ins...

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Detalles Bibliográficos
Autores principales: Thomas, Sandhya S., Dong, Yanjun, Zhang, Liping, Mitch, William E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3777429/
https://www.ncbi.nlm.nih.gov/pubmed/23515050
http://dx.doi.org/10.1038/ki.2013.97