Novel roles of Skp2 E3 ligase in cellular senescence, cancer progression, and metastasis

S-phase kinase-associated protein 2 (Skp2) belongs to the F-box protein family. It is a component of the SCF E3 ubiquitin ligase complex. Skp2 has been shown to regulate cellular proliferation by targeting several cell cycle-regulated proteins for ubiquitination and degradation, including cyclin-dep...

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Detalles Bibliográficos
Autores principales: Wang, Guocan, Chan, Chia-Hsin, Gao, Yuan, Lin, Hui-Kuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Sun Yat-sen University Cancer Center 2012
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3777478/
https://www.ncbi.nlm.nih.gov/pubmed/22200179
http://dx.doi.org/10.5732/cjc.011.10319

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3777478/
https://www.ncbi.nlm.nih.gov/pubmed/22200179
http://dx.doi.org/10.5732/cjc.011.10319

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