Mycobacterium tuberculosis mutation rate estimates from different lineages predict substantial differences in the emergence of drug resistant tuberculosis

A critical question in tuberculosis control is why some strains of Mycobacterium tuberculosis are preferentially associated with multiple drug resistances. We demonstrate that M. tuberculosis strains from Lineage 2 (East Asian lineage and Beijing sublineage) acquire drug resistances in vitro more ra...

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Detalles Bibliográficos
Autores principales: Ford, Christopher B., Shah, Rupal R., Maeda, Midori Kato, Gagneux, Sebastien, Murray, Megan B., Cohen, Ted, Johnston, James C., Gardy, Jennifer, Lipsitch, Marc, Fortune, Sarah M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3777616/
https://www.ncbi.nlm.nih.gov/pubmed/23749189
http://dx.doi.org/10.1038/ng.2656

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3777616/
https://www.ncbi.nlm.nih.gov/pubmed/23749189
http://dx.doi.org/10.1038/ng.2656

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