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Inactivation of Intergenic Enhancers by EBNA3A Initiates and Maintains Polycomb Signatures across a Chromatin Domain Encoding CXCL10 and CXCL9

Epstein-Barr virus (EBV) causes a persistent infection in human B cells by establishing specific transcription programs to control B cell activation and differentiation. Transcriptional reprogramming of EBV infected B cells is predominantly driven by the action of EBV nuclear antigens, among them th...

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Detalles Bibliográficos
Autores principales: Harth-Hertle, Marie L., Scholz, Barbara A., Erhard, Florian, Glaser, Laura V., Dölken, Lars, Zimmer, Ralf, Kempkes, Bettina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3777872/
https://www.ncbi.nlm.nih.gov/pubmed/24068939
http://dx.doi.org/10.1371/journal.ppat.1003638