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Cytokine Response Signatures in Disease Progression and Development of Severe Clinical Outcomes for Leptospirosis

BACKGROUND: The role of the immune response in influencing leptospirosis clinical outcomes is not yet well understood. We hypothesized that acute-phase serum cytokine responses may play a role in disease progression, risk for death, and severe pulmonary hemorrhage syndrome (SPHS). METHODOLOGY/PRINCI...

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Detalles Bibliográficos
Autores principales: Reis, Eliana A. G., Hagan, José E., Ribeiro, Guilherme S., Teixeira-Carvalho, Andrea, Martins-Filho, Olindo A., Montgomery, Ruth R., Shaw, Albert C., Ko, Albert I., Reis, Mitermayer G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3777885/
https://www.ncbi.nlm.nih.gov/pubmed/24069500
http://dx.doi.org/10.1371/journal.pntd.0002457