SCD1 Expression Is Dispensable for Hepatocarcinogenesis Induced by AKT and Ras Oncogenes in Mice

Increased de novo lipogenesis is one of the major metabolic events in cancer. In human hepatocellular carcinoma (HCC), de novo lipogenesis has been found to be increased and associated with the activation of AKT/mTOR signaling. In mice, overexpression of an activated form of AKT results in increased...

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Detalles Bibliográficos
Autores principales: Li, Lei, Wang, Chunmei, Calvisi, Diego F., Evert, Matthias, Pilo, Maria G., Jiang, Lijie, Yuneva, Mariia, Chen, Xin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3777889/
https://www.ncbi.nlm.nih.gov/pubmed/24069385
http://dx.doi.org/10.1371/journal.pone.0075104

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3777889/
https://www.ncbi.nlm.nih.gov/pubmed/24069385
http://dx.doi.org/10.1371/journal.pone.0075104

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