Aging-Induced Proteostatic Changes in the Rat Hippocampus Identify ARP3, NEB2 and BRAG2 as a Molecular Circuitry for Cognitive Impairment

Disturbed proteostasis as a particular phenotype of the aging organism has been advanced in C. elegans experiments and is also conceived to underlie neurodegenerative diseases in humans. Here, we investigated whether particular changes in non-disease related proteostasis can be identified in the age...

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Detalles Bibliográficos
Autores principales: Ottis, Philipp, Topic, Bianca, Loos, Maarten, Li, Ka Wan, de Souza, Angelica, Schulz, Daniela, Smit, August B., Huston, Joseph P., Korth, Carsten
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3777897/
https://www.ncbi.nlm.nih.gov/pubmed/24069387
http://dx.doi.org/10.1371/journal.pone.0075112

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3777897/
https://www.ncbi.nlm.nih.gov/pubmed/24069387
http://dx.doi.org/10.1371/journal.pone.0075112

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