TNF-α Induces Cytosolic Phospholipase A(2) Expression in Human Lung Epithelial Cells via JNK1/2- and p38 MAPK-Dependent AP-1 Activation

BACKGROUND: Cytosolic phospholipase A(2) (cPLA(2)) plays a pivotal role in mediating agonist-induced arachidonic acid (AA) release for prostaglandin (PG) synthesis during inflammation triggered by tumor necrosis factor-α (TNF-α). However, the mechanisms underlying TNF-α-induced cPLA(2) expression in...

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Detalles Bibliográficos
Autores principales: Lee, I-Ta, Lin, Chih-Chung, Cheng, Shin-Ei, Hsiao, Li-Der, Hsiao, Yu-Chun, Yang, Chuen-Mao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3777958/
https://www.ncbi.nlm.nih.gov/pubmed/24069158
http://dx.doi.org/10.1371/journal.pone.0072783

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3777958/
https://www.ncbi.nlm.nih.gov/pubmed/24069158
http://dx.doi.org/10.1371/journal.pone.0072783

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