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A Hybrid NRPS-PKS Gene Cluster Related to the Bleomycin Family of Antitumor Antibiotics in Alteromonas macleodii Strains

Although numerous marine bacteria are known to produce antibiotics via hybrid NRPS-PKS gene clusters, none have been previously described in an  Alteromonas  species. In this study, we describe in detail a novel hybrid NRPS-PKS cluster identified in the plasmid of the  Alteromonas macleodii strain A...

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Detalles Bibliográficos
Autores principales: Mizuno, Carolina Megumi, Kimes, Nikole E., López-Pérez, Mario, Ausó, Eva, Rodriguez-Valera, Francisco, Ghai, Rohit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3777966/
https://www.ncbi.nlm.nih.gov/pubmed/24069455
http://dx.doi.org/10.1371/journal.pone.0076021