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A Hybrid NRPS-PKS Gene Cluster Related to the Bleomycin Family of Antitumor Antibiotics in Alteromonas macleodii Strains
Although numerous marine bacteria are known to produce antibiotics via hybrid NRPS-PKS gene clusters, none have been previously described in an Alteromonas species. In this study, we describe in detail a novel hybrid NRPS-PKS cluster identified in the plasmid of the Alteromonas macleodii strain A...
Autores principales: | Mizuno, Carolina Megumi, Kimes, Nikole E., López-Pérez, Mario, Ausó, Eva, Rodriguez-Valera, Francisco, Ghai, Rohit |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3777966/ https://www.ncbi.nlm.nih.gov/pubmed/24069455 http://dx.doi.org/10.1371/journal.pone.0076021 |
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