Inhibition of HIV-1 Reverse Transcriptase-Catalyzed Synthesis by Intercalated DNA Benzo[a]Pyrene 7,8-Dihydrodiol-9,10-Epoxide Adducts

To aid in the characterization of the relationship of structure and function for human immunodeficiency virus type-1 reverse transcriptase (HIV-1 RT), this investigation utilized DNAs containing benzo[a]pyrene-7,8-dihydrodiol-9,10-epoxide (BPDE)-modified primers and templates as a probe of the archi...

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Detalles Bibliográficos
Autores principales: Chary, Parvathi, Beard, William A., Wilson, Samuel H., Lloyd, R. Stephen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3778021/
https://www.ncbi.nlm.nih.gov/pubmed/24069141
http://dx.doi.org/10.1371/journal.pone.0072131

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3778021/
https://www.ncbi.nlm.nih.gov/pubmed/24069141
http://dx.doi.org/10.1371/journal.pone.0072131

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