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A conserved ncRNA-binding protein recruits silencing factors to heterochromatin through an RNAi-independent mechanism

Long noncoding RNAs (lncRNAs) can trigger repressive chromatin, but how they recruit silencing factors remains unclear. In Schizosaccharomyces pombe, heterochromatin assembly on transcribed noncoding pericentromeric repeats requires both RNAi and RNAi-independent mechanisms. In Saccharomyces cerevis...

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Detalles Bibliográficos
Autores principales: Marina, Diana B., Shankar, Smita, Natarajan, Prashanthi, Finn, Kenneth J., Madhani, Hiten D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3778239/
https://www.ncbi.nlm.nih.gov/pubmed/24013500
http://dx.doi.org/10.1101/gad.226019.113