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The C terminus of p53 regulates gene expression by multiple mechanisms in a target- and tissue-specific manner in vivo
The p53 tumor suppressor is a transcription factor that mediates varied cellular responses. The C terminus of p53 is subjected to multiple and diverse post-translational modifications. An attractive hypothesis is that differing sets of combinatorial modifications therein determine distinct cellular...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory Press
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3778241/ https://www.ncbi.nlm.nih.gov/pubmed/24013501 http://dx.doi.org/10.1101/gad.224386.113 |