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The C terminus of p53 regulates gene expression by multiple mechanisms in a target- and tissue-specific manner in vivo

The p53 tumor suppressor is a transcription factor that mediates varied cellular responses. The C terminus of p53 is subjected to multiple and diverse post-translational modifications. An attractive hypothesis is that differing sets of combinatorial modifications therein determine distinct cellular...

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Detalles Bibliográficos
Autores principales:	Hamard, Pierre-Jacques, Barthelery, Nicolas, Hogstad, Brandon, Mungamuri, Sathish Kumar, Tonnessen, Crystal A., Carvajal, Luis A., Senturk, Emir, Gillespie, Virginia, Aaronson, Stuart A., Merad, Miriam, Manfredi, James J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cold Spring Harbor Laboratory Press 2013
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3778241/ https://www.ncbi.nlm.nih.gov/pubmed/24013501 http://dx.doi.org/10.1101/gad.224386.113

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