Cargando…

Epe1 recruits BET family bromodomain protein Bdf2 to establish heterochromatin boundaries

Heterochromatin spreading leads to the silencing of genes within its path, and boundary elements have evolved to constrain such spreading. In fission yeast, heterochromatin at centromeres I and III is flanked by inverted repeats termed IRCs, which are required for proper boundary functions. However,...

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Jiyong, Tadeo, Xavier, Hou, Haitong, Tu, Patricia G., Thompson, James, Yates, John R., Jia, Songtao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3778242/
https://www.ncbi.nlm.nih.gov/pubmed/24013502
http://dx.doi.org/10.1101/gad.221010.113