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Epe1 recruits BET family bromodomain protein Bdf2 to establish heterochromatin boundaries
Heterochromatin spreading leads to the silencing of genes within its path, and boundary elements have evolved to constrain such spreading. In fission yeast, heterochromatin at centromeres I and III is flanked by inverted repeats termed IRCs, which are required for proper boundary functions. However,...
Autores principales: | Wang, Jiyong, Tadeo, Xavier, Hou, Haitong, Tu, Patricia G., Thompson, James, Yates, John R., Jia, Songtao |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory Press
2013
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3778242/ https://www.ncbi.nlm.nih.gov/pubmed/24013502 http://dx.doi.org/10.1101/gad.221010.113 |
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