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Tpz1 controls a telomerase-nonextendible telomeric state and coordinates switching to an extendible state via Ccq1

Telomeres are nucleoprotein complexes comprising telomeric DNA repeats bound by the multiprotein shelterin complex. A dynamic binary switch between telomerase-extendible and telomerase-nonextendible telomeric states determines telomere length homeostasis. However, the molecular nature of the nonexte...

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Detalles Bibliográficos
Autores principales: Jun, Hyun-Ik, Liu, Jinqiang, Jeong, Heetae, Kim, Jin-Kwang, Qiao, Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3778244/
https://www.ncbi.nlm.nih.gov/pubmed/24013504
http://dx.doi.org/10.1101/gad.219485.113