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Tpz1 controls a telomerase-nonextendible telomeric state and coordinates switching to an extendible state via Ccq1
Telomeres are nucleoprotein complexes comprising telomeric DNA repeats bound by the multiprotein shelterin complex. A dynamic binary switch between telomerase-extendible and telomerase-nonextendible telomeric states determines telomere length homeostasis. However, the molecular nature of the nonexte...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Cold Spring Harbor Laboratory Press
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3778244/ https://www.ncbi.nlm.nih.gov/pubmed/24013504 http://dx.doi.org/10.1101/gad.219485.113 |