The antibody-based targeted delivery of TNF in combination with doxorubicin eradicates sarcomas in mice and confers protective immunity

BACKGROUND: Soft-tissue sarcomas are a group of malignancies of mesenchymal origin, which typically have a dismal prognosis if they reach the metastatic stage. The observation of rare spontaneous remissions in patients suffering from concomitant bacterial infections had triggered the clinical invest...

Descripción completa

Detalles Bibliográficos
Autores principales: Hemmerle, T, Probst, P, Giovannoni, L, Green, A J, Meyer, T, Neri, D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Translational Therapeutics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3778281/
https://www.ncbi.nlm.nih.gov/pubmed/23887603
http://dx.doi.org/10.1038/bjc.2013.421

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3778281/
https://www.ncbi.nlm.nih.gov/pubmed/23887603
http://dx.doi.org/10.1038/bjc.2013.421

Ejemplares similares