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The antibody-based targeted delivery of TNF in combination with doxorubicin eradicates sarcomas in mice and confers protective immunity

BACKGROUND: Soft-tissue sarcomas are a group of malignancies of mesenchymal origin, which typically have a dismal prognosis if they reach the metastatic stage. The observation of rare spontaneous remissions in patients suffering from concomitant bacterial infections had triggered the clinical invest...

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Detalles Bibliográficos
Autores principales:	Hemmerle, T, Probst, P, Giovannoni, L, Green, A J, Meyer, T, Neri, D
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2013
Materias:	Translational Therapeutics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3778281/ https://www.ncbi.nlm.nih.gov/pubmed/23887603 http://dx.doi.org/10.1038/bjc.2013.421

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