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Proline-rich tyrosine kinase 2 and its phosphorylated form pY881 are novel prognostic markers for non-small-cell lung cancer progression and patients' overall survival

BACKGROUND: Our previous study revealed that proline-rich tyrosine kinase 2 (Pyk2) is implicated in both anchorage-independent growth and anoikis resistance in lung cancer cells. This study aims to explore the expression and clinical significance of Pyk2 and its phosphorylated forms in non-small-cel...

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Detalles Bibliográficos
Autores principales: Kuang, B-H, Zhang, M-Q, Xu, L-H, Hu, L-J, Wang, H-B, Zhao, W-F, Du, Y, Zhang, X
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3778294/
https://www.ncbi.nlm.nih.gov/pubmed/23922106
http://dx.doi.org/10.1038/bjc.2013.439