Agonists and antagonists induce different palonosetron dissociation rates in 5-HT(3)A and 5-HT(3)AB receptors()

Palonosetron is a potent 5-HT(3) receptor antagonist with a unique structure and some unusual properties. Here we explore the properties of palonosetron at heterologously expressed 5-HT(3)A and 5-HT(3)AB receptors. We used receptors expressed in HEK293 cells, and functionally analysed them using a m...

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Detalles Bibliográficos
Autores principales: Lummis, Sarah C.R., Thompson, Andrew J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Pergamon Press 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3778450/
https://www.ncbi.nlm.nih.gov/pubmed/23747573
http://dx.doi.org/10.1016/j.neuropharm.2013.05.010

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3778450/
https://www.ncbi.nlm.nih.gov/pubmed/23747573
http://dx.doi.org/10.1016/j.neuropharm.2013.05.010

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