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An experimental test on the probability of extinction of new genetic variants

In 1927, J.B.S. Haldane reasoned that the probability of fixation of new beneficial alleles is twice their fitness effect. This result, later generalized by M. Kimura, has since become the cornerstone of modern population genetics. There is no experimental test of Haldane’s insight that new benefici...

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Detalles Bibliográficos
Autores principales: Chelo, Ivo M., Nédli, Judit, Gordo, Isabel, Teotónio, Henrique
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3778522/
https://www.ncbi.nlm.nih.gov/pubmed/24030070
http://dx.doi.org/10.1038/ncomms3417