Human cap methyltransferase (RNMT) N-terminal non-catalytic domain mediates recruitment to transcription initiation sites

Gene expression in eukaryotes is dependent on the mRNA methyl cap which mediates mRNA processing and translation initiation. Synthesis of the methyl cap initiates with the addition of 7-methylguanosine to the initiating nucleotide of RNA pol II (polymerase II) transcripts, which occurs predominantly...

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Detalles Bibliográficos
Autores principales: Aregger, Michael, Cowling, Victoria H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3778707/
https://www.ncbi.nlm.nih.gov/pubmed/23863084
http://dx.doi.org/10.1042/BJ20130378

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3778707/
https://www.ncbi.nlm.nih.gov/pubmed/23863084
http://dx.doi.org/10.1042/BJ20130378

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