Efficient TGFβ-induced epithelial–mesenchymal transition depends on hyaluronan synthase HAS2

Epithelial–mesenchymal transition (EMT) is a developmental program, which can be adopted by cancer cells to increase their migration and ability to form metastases. Transforming growth factor β (TGFβ) is a well-studied inducer of EMT. We demonstrate that TGFβ potently stimulates hyaluronan synthesis...

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Detalles Bibliográficos
Autores principales: Porsch, H, Bernert, B, Mehić, M, Theocharis, A D, Heldin, C-H, Heldin, P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3778714/
https://www.ncbi.nlm.nih.gov/pubmed/23108409
http://dx.doi.org/10.1038/onc.2012.475

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3778714/
https://www.ncbi.nlm.nih.gov/pubmed/23108409
http://dx.doi.org/10.1038/onc.2012.475

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