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Quantal and graded stimulation of B lymphocytes as alternative strategies for regulating adaptive immune responses

Lymphocytes undergo a typical response pattern following stimulation in vivo: they proliferate, differentiate to effector cells, cease dividing and predominantly die, leaving a small proportion of long-lived memory and effector cells. This pattern results from cell-intrinsic processes following acti...

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Detalles Bibliográficos
Autores principales: Hawkins, E.D., Turner, M.L., Wellard, C.J., Zhou, J.H.S., Dowling, M.R., Hodgkin, P.D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3778729/
https://www.ncbi.nlm.nih.gov/pubmed/24009041
http://dx.doi.org/10.1038/ncomms3406