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Regulation of the brain isoprenoids farnesyl- and geranylgeranylpyrophosphate is altered in male Alzheimer patients

Post-translational modification of small GTPases by farnesyl- (FPP) and geranylgeranylpyrophosphate (GGPP) has generated much attention due to their potential contribution to cancer, cardiovascular and neurodegenerative diseases. Prenylated proteins have been identified in numerous cell functions an...

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Detalles Bibliográficos
Autores principales: Eckert, Gunter P., Hooff, Gero P., Strandjord, Dana M., Igbavboa, Urule, Volmer, Dietrich A., Müller, Walter E., Wood, W. Gibson
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Academic Press 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3778879/
https://www.ncbi.nlm.nih.gov/pubmed/19464372
http://dx.doi.org/10.1016/j.nbd.2009.05.005