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Widespread DNA hypomethylation at gene enhancer regions in placentas associated with early-onset pre-eclampsia

Pre-eclampsia is a serious complication of pregnancy that can affect both maternal and fetal outcomes. Early-onset pre-eclampsia (EOPET) is a severe form of pre-eclampsia that is associated with altered physiological characteristics and gene expression in the placenta. DNA methylation is a relativel...

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Detalles Bibliográficos
Autores principales: Blair, John D., Yuen, Ryan K.C., Lim, Brendan K., McFadden, Deborah E., von Dadelszen, Peter, Robinson, Wendy P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3779005/
https://www.ncbi.nlm.nih.gov/pubmed/23770704
http://dx.doi.org/10.1093/molehr/gat044