Cargando…

Physiology of endothelin in producing myocardial perfusion heterogeneity: A mechanistic study using darusentan and positron emission tomography

BACKGROUND: Heterogeneity of resting perfusion may be due in part to up-regulation of coronary vasoconstriction via endothelin (ET) type A receptors, as homogeneity increases during subsequent vasodilatory hyperemia. Therefore, we conducted a mechanistic study using an ET receptor antagonist to dete...

Descripción completa

Detalles Bibliográficos
Autores principales: Johnson, Nils P., Gould, K. Lance
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3779022/
https://www.ncbi.nlm.nih.gov/pubmed/23842710
http://dx.doi.org/10.1007/s12350-013-9756-5