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Physiology of endothelin in producing myocardial perfusion heterogeneity: A mechanistic study using darusentan and positron emission tomography
BACKGROUND: Heterogeneity of resting perfusion may be due in part to up-regulation of coronary vasoconstriction via endothelin (ET) type A receptors, as homogeneity increases during subsequent vasodilatory hyperemia. Therefore, we conducted a mechanistic study using an ET receptor antagonist to dete...
Autores principales: | Johnson, Nils P., Gould, K. Lance |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer US
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3779022/ https://www.ncbi.nlm.nih.gov/pubmed/23842710 http://dx.doi.org/10.1007/s12350-013-9756-5 |
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