Exploring Histidine Conformations in the M2 Channel Lumen of the Influenza A Virus at Neutral pH via Molecular Simulations

[Image: see text] The pH-regulated M2 proton channel from the influenza A virus has a His-tetrad in its transmembrane (TM) domain that is essential for proton conduction. At neutral pH, the tetrad has been observed in two distinct configurations, the “His-box” and “dimer-of-dimers”, with similar bac...

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Detalles Bibliográficos
Autores principales: Dong, Hao, Fiorin, Giacomo, DeGrado, William F., Klein, Michael L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2013
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3779100/
https://www.ncbi.nlm.nih.gov/pubmed/24069512
http://dx.doi.org/10.1021/jz401672h

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3779100/
https://www.ncbi.nlm.nih.gov/pubmed/24069512
http://dx.doi.org/10.1021/jz401672h

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