Cargando…
Exploring Histidine Conformations in the M2 Channel Lumen of the Influenza A Virus at Neutral pH via Molecular Simulations
[Image: see text] The pH-regulated M2 proton channel from the influenza A virus has a His-tetrad in its transmembrane (TM) domain that is essential for proton conduction. At neutral pH, the tetrad has been observed in two distinct configurations, the “His-box” and “dimer-of-dimers”, with similar bac...
| Autores principales: | , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical Society
2013
|
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3779100/ https://www.ncbi.nlm.nih.gov/pubmed/24069512 http://dx.doi.org/10.1021/jz401672h |