Cargando…
T Cell and Dendritic Cell Abnormalities Synergize to Expand Pro-Inflammatory T Cell Subsets Leading to Fatal Autoimmunity in B6.NZBc1 Lupus-Prone Mice
We have previously shown that B6 congenic mice with a New Zealand Black chromosome 1 (c1) 96-100 cM interval produce anti-nuclear Abs and that at least two additional genetic loci are required to convert this subclinical disease to fatal glomerulonephritis in mice with a c1 70-100 cM interval (c1(70...
Autores principales: | Talaei, Nafiseh, Cheung, Yui-Ho, Landolt-Marticorena, Carolina, Noamani, Babak, Li, Timothy, Wither, Joan E. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3779178/ https://www.ncbi.nlm.nih.gov/pubmed/24073245 http://dx.doi.org/10.1371/journal.pone.0075166 |
Ejemplares similares
-
Genetic polymorphisms leading to altered T-cell and dendritic cell function cooperate to produce expansion of proinflammatory T-cell subsets in NZB c1 congenic mice
por: Talaei, N, et al.
Publicado: (2012) -
Impaired B cell anergy is not sufficient to breach tolerance to nuclear antigen in Vκ8/3H9 lupus-prone mice
por: Manion, Kieran P., et al.
Publicado: (2020) -
A discrete cluster of urinary biomarkers discriminates between active systemic lupus erythematosus patients with and without glomerulonephritis
por: Landolt-Marticorena, Carolina, et al.
Publicado: (2016) -
Presence of an interferon signature in individuals who are anti-nuclear antibody positive lacking a systemic autoimmune rheumatic disease diagnosis
por: Wither, Joan, et al.
Publicado: (2017) -
Identification of a neutrophil-related gene expression signature that is enriched in adult systemic lupus erythematosus patients with active nephritis: Clinical/pathologic associations and etiologic mechanisms
por: Wither, Joan E., et al.
Publicado: (2018)