Quantitative Receptor-Based Imaging of Tumor Proliferation with the Sigma-2 Ligand [(18)F]ISO-1

The sigma-2 receptor is expressed in higher density in proliferating (P) tumor cells versus quiescent (Q) tumor cells, thus providing an attractive target for imaging the proliferative status (i.e., P:Q ratio) of solid tumors. Here we evaluate the utility of the sigma-2 receptor ligand 2-(2-[(18)F]f...

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Detalles Bibliográficos
Autores principales: Shoghi, Kooresh I., Xu, Jinbin, Su, Yi, He, June, Rowland, Douglas, Yan, Ying, Garbow, Joel R., Tu, Zhude, Jones, Lynne A., Higashikubo, Ryuji, Wheeler, Kenneth T., Lubet, Ronald A., Mach, Robert H., You, Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3779213/
https://www.ncbi.nlm.nih.gov/pubmed/24073202
http://dx.doi.org/10.1371/journal.pone.0074188

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3779213/
https://www.ncbi.nlm.nih.gov/pubmed/24073202
http://dx.doi.org/10.1371/journal.pone.0074188

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