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Increased Neurofilament Light Chain Blood Levels in Neurodegenerative Neurological Diseases

OBJECTIVE: Neuronal damage is the morphological substrate of persisting neurological disability. Neurofilaments (Nf) are cytoskeletal proteins of neurons and their release into cerebrospinal fluid has shown encouraging results as a biomarker for neurodegeneration. This study aimed to validate the qu...

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Detalles Bibliográficos
Autores principales: Gaiottino, Johanna, Norgren, Niklas, Dobson, Ruth, Topping, Joanne, Nissim, Ahuva, Malaspina, Andrea, Bestwick, Jonathan P., Monsch, Andreas U., Regeniter, Axel, Lindberg, Raija L., Kappos, Ludwig, Leppert, David, Petzold, Axel, Giovannoni, Gavin, Kuhle, Jens
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3779219/
https://www.ncbi.nlm.nih.gov/pubmed/24073237
http://dx.doi.org/10.1371/journal.pone.0075091