Cargando…
Increased Neurofilament Light Chain Blood Levels in Neurodegenerative Neurological Diseases
OBJECTIVE: Neuronal damage is the morphological substrate of persisting neurological disability. Neurofilaments (Nf) are cytoskeletal proteins of neurons and their release into cerebrospinal fluid has shown encouraging results as a biomarker for neurodegeneration. This study aimed to validate the qu...
Autores principales: | Gaiottino, Johanna, Norgren, Niklas, Dobson, Ruth, Topping, Joanne, Nissim, Ahuva, Malaspina, Andrea, Bestwick, Jonathan P., Monsch, Andreas U., Regeniter, Axel, Lindberg, Raija L., Kappos, Ludwig, Leppert, David, Petzold, Axel, Giovannoni, Gavin, Kuhle, Jens |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3779219/ https://www.ncbi.nlm.nih.gov/pubmed/24073237 http://dx.doi.org/10.1371/journal.pone.0075091 |
Ejemplares similares
-
Neurofilament light chain: A prognostic biomarker in amyotrophic lateral sclerosis
por: Lu, Ching-Hua, et al.
Publicado: (2015) -
Plasma neurofilament heavy chain levels and disease progression in amyotrophic lateral sclerosis: insights from a longitudinal study
por: Lu, Ching-Hua, et al.
Publicado: (2015) -
Fingolimod and CSF neurofilament light chain levels in relapsing-remitting multiple sclerosis
por: Kuhle, Jens, et al.
Publicado: (2015) -
Long-term prognostic value of longitudinal measurements of blood neurofilament levels
por: Häring, Dieter A., et al.
Publicado: (2020) -
Blood neurofilament light as a potential endpoint in Phase 2 studies in MS
por: Sormani, Maria Pia, et al.
Publicado: (2019)