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Doublecortin Knockout Mice Show Normal Hippocampal-Dependent Memory Despite CA3 Lamination Defects

Mutations in the human X-linked doublecortin gene (DCX) cause major neocortical disorganization associated with severe intellectual disability and intractable epilepsy. Although Dcx knockout (KO) mice exhibit normal isocortical development and architecture, they show lamination defects of the hippoc...

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Detalles Bibliográficos
Autores principales: Germain, Johanne, Bruel-Jungerman, Elodie, Grannec, Gael, Denis, Cécile, Lepousez, Gabriel, Giros, Bruno, Francis, Fiona, Nosten-Bertrand, Marika
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3779246/
https://www.ncbi.nlm.nih.gov/pubmed/24073232
http://dx.doi.org/10.1371/journal.pone.0074992