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Unravelling the connection between metabolism and tumorigenesis through studies of the liver kinase B1 tumour suppressor
The liver kinase B1 (LKB1) tumour suppressor functions as a master regulator of growth, metabolism and survival in cells, which is frequently mutated in sporadic human non-small cell lung and cervical cancers. LKB1 functions as a key upstream activator of the AMP-activated protein kinase (AMPK), a c...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Medknow Publications & Media Pvt Ltd
2013
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3779404/ https://www.ncbi.nlm.nih.gov/pubmed/24082825 http://dx.doi.org/10.4103/1477-3163.116323 |