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Inhibition of endotrophin, a cleavage product of collagen VI, confers cisplatin sensitivity to tumours

Endotrophin is a cleavage product of collagenVIα3 (COL6A3). Here, we explore the relationship between thiazolidinediones (TZDs), endotrophin and cisplatin resistance in the context of a mammary tumour model. COL6A3 levels are increased in response to cisplatin exposure in tumours. Endotrophin, in tu...

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Detalles Bibliográficos
Autores principales: Park, Jiyoung, Morley, Thomas S, Scherer, Philipp E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: WILEY-VCH Verlag 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3779453/
https://www.ncbi.nlm.nih.gov/pubmed/23629957
http://dx.doi.org/10.1002/emmm.201202006